Imagine a painful, chronic infection that has no cure and affects the majority of people worldwide. It is highly contagious and has few treatments beyond palliative care. Primary herpetic gingivostomatitis is that condition.

What is primary herpetic gingivostomatitis?

Primary herpetic gingivostomatitis (also referred to as orolabial herpes) is the first and often most painful iteration of cold sores. Caused by the HSV1 (herpes simplex virus type 1), this infection occurs in everyone from babies to older adults.

The sores that appear as a result of primary herpetic gingivostomatitis are circled in red and can be yellow or gray in the middle. Starting as multiple vesicles filled with fluid, they appear most frequently inside the mouth. The vesicles break open and form painful ulcers. Outbreaks can last for up to ten days, with sores that are irritated and itchy as they begin to heal.

After the appearance of primary herpetic gingivostomatitis, the following infections will most likely appear as cold sores outside of the mouth. It is important to note that neither cold sores not primary herpetic gingivostomatitis are caused by the same virus that causes genital herpes (herpes simplex virus type 2, or HSV2).

Primary herpetic gingivostomatitis symptoms

To begin, there is usually a prodromal phase where you may feel a prickling or burning sensation in the mouth and on the lips. This does not affect everyone, and babies or young children may not be able to explain or identify this symptom.

The most common symptoms include the following:

  • Fever in the days leading up to an outbreak (and, in some cases, continuing through the outbreak)
  • Swollen gums
  • Bleeding gums
  • Swollen lymph nodes
  • Headache
  • Fatigue
  • Loss of appetite
  • Sore throat
  • Pain when swallowing
  • Halitosis (bad breath)
  • General malaise or feeling poorly

When this first outbreak occurs in children, they may experience vesicles not only in their mouth on their gums but also on their lips and cheeks. Lesions on the face may be incredibly painful. Young children and babies may also drool excessively, a symptom that is sometimes confused with the drooling associated with teething.

Diagnosis of this condition is simple. Once a lesion appears, your doctor swabs it and tests for the presence of the herpes simplex virus 1. While lesions may resemble other oral conditions, if HSV1 is present, it is diagnosed as primary herpetic gingivostomatitis.

Is primary herpetic gingivostomatitis contagious?

HSV1 is very common around the globe, with an estimated two-thirds of the population infected. HSV2 is less common, and the incidence of both appears to be decreasing.

Both viruses are highly contagious and often